1H-Pyrrole-2,5-dione, 1-[4-(phenylazo)phenyl]- - Names and Identifiers
1H-Pyrrole-2,5-dione, 1-[4-(phenylazo)phenyl]- - Physico-chemical Properties
Molecular Formula | C16H11N3O2
|
Molar Mass | 277.28 |
Density | 1.26±0.1 g/cm3(Predicted) |
Melting Point | 162-165°C |
Boling Point | 475.1±28.0 °C(Predicted) |
BRN | 236610 |
pKa | -2.37±0.20(Predicted) |
Storage Condition | Room Temprature |
MDL | MFCD00005506 |
1H-Pyrrole-2,5-dione, 1-[4-(phenylazo)phenyl]- - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
TSCA | Yes |
1H-Pyrrole-2,5-dione, 1-[4-(phenylazo)phenyl]- - Introduction
4-phenyllazomaleinanil is an antibiotic with the chemical name 4-amino-n-(4,6-dimethyl-2-pyrazinyl)-3-nitroaniline.
Nature:
-Appearance: White or yellowish crystalline powder
-Solubility: Slightly soluble in water, soluble in organic solvents such as methanol and dichloromethane
-Melting point: About 170 ° C
-Stability: stable at room temperature, avoid direct sunlight and humid environment
Use:
-Antibiotics: 4-Phenylazomaleinanil is commonly used in the treatment of clinical infections, especially against gram-positive bacteria have strong antibacterial activity.
-Veterinary medicine: 4-Phenylazomaleinanil is also widely used as an antibiotic additive for livestock and poultry to prevent and treat infectious diseases in livestock and poultry.
Preparation Method:
The preparation method of 4-Phenylazomaleinanil generally includes the following steps:
1. P-Nitroaniline is obtained by the reaction of sodium nitrite and aniline.
2. The p-nitroaniline was dissolved with methanol and reacted with 4,6-dimethyl-2-pyrazinamine to yield 4-amino-N-(4,6-dimethyl-2-pyrazinyl)-3-Nitroaniline.
3. Finally, the pure product of 4-phenyllazomaleinanil was obtained by crystallization and purification.
Safety Information:
- 4-Phenylazomaleinanil is a toxic substance and should avoid inhalation of dust or contact with skin and eyes.
-Wear protective glasses, gloves and lab coat when operating or touching 4-Phenylazomaleinanil.
-In storage and use, please pay attention to follow the safety procedures, and keep it in a dry, cool place, away from fire and oxidizing agents.
Please note that the information provided here is for reference only, and the specific application and safety operation should be carried out according to the specific situation and experimental requirements. Before using 4-Phenylazomaleinanil, it is best to consult a professional and read the product manual carefully.
Last Update:2024-04-09 21:31:56